Publications

Selected Publications

  • Jin, L., Sullivan, H. A., Zhu, M., Lavin, T. K., Matsuyama, M., Fu, X., Lea, N. E., Xu, R., Hou, Y., Rutigliani, L., Pruner, M., Babcock, K. R., Ip, J. P. K., Hu, M., Daigle, T. L., Zeng, H., Sur, M., Feng, G., & Wickersham, I. R. (2024). Long-term labeling and imaging of synaptically connected neuronal networks in vivo using double-deletion-mutant rabies viruses. Nature Neuroscience, 27(2), 373–383. Click here
  • Chai, Y., Lee, S. S. Y., Shillington, A., Du, X., Fok, C. K. M., Yeung, K. C., Siu, G. K. Y., Yuan, S., Zheng, Z., Tsang, H. W. S., Gu, S., Chen, Y., Ye, T., & Ip, J. P. K. (2023). Non-canonical C-terminal variant of MeCP2 R344W exhibits enhanced degradation rate. IBRO Neuroscience Reports, 15, 218–224. Click here
  • Zhou, Z., Yip, H. M., Tsimring, K., Sur, M., Ip, J. P. K.#, & Tin, C#. (2023). Effective and efficient neural networks for spike inference from in vivo calcium imaging. Cell Reports Methods. Click here
    • #Co-correspondence
  • Guan, M., Chai, Y., Yi, R., Chen, Y., Ip, J. P. K., Ye, T., & Chen, Y. (2023). Generation of a homozygous ABCA7-knockout human iPSC line using the CRISPR/Cas9 system. Stem Cell Research, 66, 103000–. Click here
  • Li, X., Chen, S.-C., & Ip, J. P. K. (2022). Diverse and Composite Roles of miRNA in Non-Neuronal Cells and Neuronal Synapses in Alzheimer’s Disease. Biomolecules (Basel, Switzerland), 12(10), 1505–. Click here
  • Yildirim, M., Delepine, C., Feldman, D., Pham, V. A., Chou, S., Ip, J., Nott, A., Tsai, L.-H., Ming, G.-L., So, P. T., & Sur, M. (2022). Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome. eLife, 11. Click here
  • Chow, C. F. W., Guo, X., Asthana, P., Zhang, S., Wong, S. K. K., Fallah, S., Che, S., Gurung, S., Wang, Z., Lee, K. B., Ge, X., Yuan, S., Xu, H., Ip, J. P. K., Jiang, Z., Zhai, L., Wu, J., Zhang, Y., Mahato, A. K., … Wong, H. L. X. (2022). Body weight regulation via MT1-MMP-mediated cleavage of GFRAL. Nature Metabolism, 4(2), 203–212. Click here
  • Jenks, K. R., Tsimring, K., Ip, J. P. K., Zepeda, J. C., & Sur, M. (2021). Heterosynaptic Plasticity and the Experience-Dependent Refinement of Developing Neuronal Circuits. Frontiers in Neural Circuits, 15, 803401–803401. Click here

Before 2020

  • Su, Y.T., Lau, S.F., Ip, J.P., Cheung, K., Cheung, T.H.T., Fu, A.K.Y., Ip, N.Y. α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis. Proc. Natl. Acad. Sci., 2019, Jul 2; 116(27):13651-13660 Click here
  • El-Boustani, S.*, Ip, J.P.*, Breton-Provencher, V., Knott, G., Okuno, H., Bito, H., Sur, M. “Locally coordinated synaptic plasticity shapes cell-wide plasticity of visual cortex neurons in vivo” Science, 2018, Vol. 360, Issue 6395, pp. 1349-1354. Click here
  • Ip, J.P.*, Nagakura, I.*, Petravicz, J., Li,K., Wiemer, E.A.C., Sur, M. “Major vault protein, a candidate gene in 16p11.2 microdeletion syndrome, is required for the homeostatic regulation of visual cortical plasticity” Journal of Neuroscience, 2018, Apr 18;38(16):3890-3900. Click here
  • Ip, J.P., Mellios, N., Sur, M “Rett Syndrome: genetic, molecular and functional insights into multi-stage dysfunction” Nature Review Neuroscience, 2018, Jun; 19(6): 368-382. Review. Click here
  • Mellios, N.*, Feldman, D.*, Sheridan, S.D.*, Ip, J.P.*, Kwok, S., Amoah, S.K., Rosen, B., Rodriguez, B.A., Crawford, B., Swaminathan, R., Chou, S., Li, L., Ziats, M., Ernst, C., Jaenisch, R., Haggarty, S., Sur, M. “MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling” Molecular Psychiatry, 2018, Apr;23(4):1051-1065. Click here
    • *Equal contribution
    • Featured image: Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors. Molecular Psychiatry. 2018 Apr; 23(4):791. Click here
  • Ye, T., Ip, J.P., Fu, A.K., Ip, N.Y. “Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex” Nature Communications, 2014,5; 5: 4826 Click here
  • Tang, J., Ip, J.P., Ye, T., Ng, Y.P., Yung, W.H., Wu, Z., Fang, W., Fu, A.K., Ip, N.Y. “Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition” Journal of Neuroscience, 2014, 28; 34(22): 7425-36 Click here
  • Ip, J.P., Fu, A. K., Ip, N. Y. “CRMP2: Functional Roles in Neural Development and Therapeutic Potential in Neurological Diseases” The Neuroscientist, 2014, 20(6): 589-98. Review. Click here
  • Noçon, A.L., Ip, J.P., Terry, R., Lim, S.L., Getts, D.R., Müller, M., Hofer, M.J., King, N.J., Campbell, I.L. “The bacteriostatic protein lipocalin 2 is induced in the central nervous system of mice with west Nile virus encephalitis” Journal of Virology, 2013, 88(1): 679-89 Click here
  • Chen, Y., Fu, W.Y., Ip, J.P., Ye, T., Fu, A.K., Chao, M.V., Ip, N.Y. “Ankyrin Repeat-Rich Membrane Spanning Protein (Kidins220) Is Required for Neurotrophin and Ephrin Receptor-Dependent Dendrite Development” Journal of Neuroscience, 2012, 32(24): 8263-8269 Click here
  • Ip, J.P.*, Shi, L.*, Chen, Y., Itoh, Y., Fu, A. W., Betz, A., Yung, W. H., Gotoh, Y., Fu, A. K., Ip, N. Y. “α2-chimaerin controls neuronal migration and functioning of cerebral cortex through CRMP-2” Nature Neuroscience, 2012, (15) 39–47  (F1000 3 stars)Click here
  • Ip, J. P.*, Nocon, A. L.*, Hofer, M. J., Lim, S. L., Muller, M., Campbell, I. L. “Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration” J Neuroinflammation, 2011,8 (1) 124. Click here
    • *Equal contribution
  • Fang, W. Q., Ip, J. P., Li, R., Ng, Y. P., Lin, S. C., Chen, Y., Fu, A. K., Ip, N. Y. “Cdk5-mediated phosphorylation of axin directs axon formation during cerebral cortex development” Journal of Neuroscience, 2011, 31 (38) 13613-24 Click here
  • Farghaian, H., Chen, Y., Fu, A. W., Fu, A. K., Ip, J. P., Ip, N. Y., Turnley, A. M., Cole, A. R. “Scapinin-induced inhibition of axon elongation is attenuated by phosphorylation and translocation to the cytoplasm” J Biol Chem, 2011, 286 (22) 19724-34 Click here